Description
AZD-3463 is a potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor that displays ability to overcome acquired resistance to Crizotinib (Cat. No.1934).
AZD-3463 is a potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor that displays ability to overcome acquired resistance to Crizotinib (Cat. No.1934).
Alternate Name/Synonyms: 2-Pyrimidinamine, N-[4-(4-amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1356962-20-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₄H₂₅ClN₆O
Molecular Weight: 448.95
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~20 mg/ml)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor
MDL Number: N/A
PubChem CID: 56599293
SMILES: COC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
InChi: InChI=1S/C24H25ClN6O/c1-32-22-12-16(31-10-8-15(26)9-11-31)6-7-21(22)29-24-28-14-19(25)23(30-24)18-13-27-20-5-3-2-4-17(18)20/h2-7,12-15,27H,8-11,26H2,1H3,(H,28,29,30)
InChi Key: GCYIGMXOIWJGBU-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20 ̊C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |