AZD-4547 | 9403

AZD-4547 is a novel and selective inhibitor of the FGFR1, 2, and 3 tyrosine kinases. It binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and thus resulting in the inhibition of tumor cell proliferation and tumor cell death.

AZD-4547 is a novel and selective inhibitor of the FGFR1, 2, and 3 tyrosine kinases. It binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and thus resulting in the inhibition of tumor cell proliferation and tumor cell death.

9403 | AZD-4547 DataSheet

Alternate Name/Synonyms: N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1035270-39-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₆H₃₃N₅O₃

Molecular Weight: 463.57

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>80 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective inhibitor of the FGFR1, 2, and 3 tyrosine kinases

MDL Number: N/A

PubChem CID: 51039095

SMILES: CC1CN(CC(N1)C)C2=CC=C(C=C2)C(=O)NC3=NNC(=C3)CCC4=CC(=CC(=C4)OC)OC

InChi: InChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21(29-30-25)8-5-19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,(H2,28,29,30,32)/t17-,18+

InChi Key: VRQMAABPASPXMW-HDICACEKSA-N