AZD-5904 | B2598

AZD-5904 is a potent and irreversible inhibitor of human myeloperoxidase (MPO) (IC₅₀ = 140 nM). Displays similar potency in mouse and rat enzymes.

AZD-5904 is a potent and irreversible inhibitor of human myeloperoxidase (MPO) (IC₅₀ = 140 nM). Displays similar potency in mouse and rat enzymes.

B2598 | AZD-5904 DataSheet

Alternate Name/Synonyms: AZ1, (S)-3-((tetrahydrofuran-2-yl)methyl)-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one, TX4, AZD5904

Appearance: Beige to light yellow solid

Formulation:

CAS Number: 618913-30-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₀H₁₂N₄O₂S

Molecular Weight: 252.29

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: >100 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent myeloperoxidase (MPO) Inhibitor

MDL Number:

PubChem CID: 10264211

SMILES: O=C1NC(N(C[C@H]2OCCC2)C3=C1NC=N3)=S

InChi: InChI=1S/C10H12N4O2S/c15-9-7-8(12-5-11-7)14(10(17)13-9)4-6-2-1-3-16-6/h5-6H,1-4H2,(H,11,12)(H,13,15,17)/t6-/m0/s1

InChi Key: RSPDBEVKURKEII-LURJTMIESA-N