Description
AZD-5904 is a potent and irreversible inhibitor of human myeloperoxidase (MPO) (IC₅₀ = 140 nM). Displays similar potency in mouse and rat enzymes.
AZD-5904 is a potent and irreversible inhibitor of human myeloperoxidase (MPO) (IC₅₀ = 140 nM). Displays similar potency in mouse and rat enzymes.
Alternate Name/Synonyms: AZ1, (S)-3-((tetrahydrofuran-2-yl)methyl)-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one, TX4, AZD5904
Appearance: Beige to light yellow solid
Formulation:
CAS Number: 618913-30-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₀H₁₂N₄O₂S
Molecular Weight: 252.29
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: >100 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent myeloperoxidase (MPO) Inhibitor
MDL Number:
PubChem CID: 10264211
SMILES: O=C1NC(N(C[C@H]2OCCC2)C3=C1NC=N3)=S
InChi: InChI=1S/C10H12N4O2S/c15-9-7-8(12-5-11-7)14(10(17)13-9)4-6-2-1-3-16-6/h5-6H,1-4H2,(H,11,12)(H,13,15,17)/t6-/m0/s1
InChi Key: RSPDBEVKURKEII-LURJTMIESA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |