AZD1208 | 2719

AZD1208 is a potent and highly selective pan-Pim Kinase inhibitor. It inhibits Pim-1,-2, and -3 kinases at <5 nM or <150 nM in enzyme and cell assays, respectively. Displays potent anticancer activities.

AZD1208 is a potent and highly selective pan-Pim Kinase inhibitor. It inhibits Pim-1,-2, and -3 kinases at <5 nM or <150 nM in enzyme and cell assays, respectively. Displays potent anticancer activities.

2719 | AZD1208 DataSheet

Alternate Name/Synonyms: 5-[[2-[(3R)-3-Aminopiperidin-1-yl]biphenyl-3-yl]methylidene]-1,3-thiazolidine-2,4-dione

Appearance: Pale yellow solid

Formulation: N/A

CAS Number: 1204144-28-4

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₁N₃O₂S

Molecular Weight: 379.48

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A pan-Pim kinase inhibitor

MDL Number: N/A

PubChem CID: 58423153

SMILES: C1CC(CN(C1)C2=C(C=CC=C2C=C3C(=O)NC(=O)S3)C4=CC=CC=C4)N

InChi: InChI=1S/C21H21N3O2S/c22-16-9-5-11-24(13-16)19-15(12-18-20(25)23-21(26)27-18)8-4-10-17(19)14-6-2-1-3-7-14/h1-4,6-8,10,12,16H,5,9,11,13,22H2,(H,23,25,26)/b18-12-/t16-/m1/s1

InChi Key: MCUJKPPARUPFJM-UWCCDQBKSA-N