Description
AZD1208 is a potent and highly selective pan-Pim Kinase inhibitor. It inhibits Pim-1,-2, and -3 kinases at <5 nM or <150 nM in enzyme and cell assays, respectively. Displays potent anticancer activities.
AZD1208 is a potent and highly selective pan-Pim Kinase inhibitor. It inhibits Pim-1,-2, and -3 kinases at <5 nM or <150 nM in enzyme and cell assays, respectively. Displays potent anticancer activities.
Alternate Name/Synonyms: 5-[[2-[(3R)-3-Aminopiperidin-1-yl]biphenyl-3-yl]methylidene]-1,3-thiazolidine-2,4-dione
Appearance: Pale yellow solid
Formulation: N/A
CAS Number: 1204144-28-4
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₁N₃O₂S
Molecular Weight: 379.48
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A pan-Pim kinase inhibitor
MDL Number: N/A
PubChem CID: 58423153
SMILES: C1CC(CN(C1)C2=C(C=CC=C2C=C3C(=O)NC(=O)S3)C4=CC=CC=C4)N
InChi: InChI=1S/C21H21N3O2S/c22-16-9-5-11-24(13-16)19-15(12-18-20(25)23-21(26)27-18)8-4-10-17(19)14-6-2-1-3-7-14/h1-4,6-8,10,12,16H,5,9,11,13,22H2,(H,23,25,26)/b18-12-/t16-/m1/s1
InChi Key: MCUJKPPARUPFJM-UWCCDQBKSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |