Description
Azeliragon is a potent RAGE (the receptor for advanced glycation end products) inhibitor. It has been evaluated for potential treatment for patients with mild-to-moderate Alzheimer's disease (AD). Azeliragon decreases brain amyloid in mice and improves their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy.
Azeliragon is a potent RAGE (the receptor for advanced glycation end products) inhibitor. It has been evaluated for potential treatment for patients with mild-to-moderate Alzheimer's disease (AD). Azeliragon decreases brain amyloid in mice and improves their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy.
Alternate Name/Synonyms: 3-(4-(2-butyl-1-(4-(4-chlorophenoxy)phenyl)-1H-imidazol-4-yl)phenoxy)-N,N-diethylpropan-1-amine; TTP488; TTP-488
Appearance: Crystalline Solid
Formulation: N/A
CAS Number: 603148-36-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₂H₃₈ClN₃O₂
Molecular Weight: 532.12
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>5 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent RAGE (the receptor for advanced glycation end products) inhibitor.
MDL Number:
PubChem CID: 11180124
SMILES: CCCCC1=NC(=CN1C2=CC=C(C=C2)OC3=CC=C(C=C3)Cl)C4=CC=C(C=C4)OCCCN(CC)CC
InChi: 1S/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3
InChi Key: KJNNWYBAOPXVJY-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |