B7-1/CD80 polyclonal Antibody | BS65576

B7-1/CD80 polyclonal Antibody | BS65576 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse,

Application: WB,

Application Range: WB=1:500-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background: CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: B7-1/CD80 polyclonal Antibody detects endogenous levels of B7-1/CD80 protein.

Molecular Weight: ~60kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Activation B7-1 antigen; B lymphocyte activation antigen B7; B7; B7-1; B7-1 antigen; BB1; CD28 antigen ligand 1; CD28LG; CD28LG1; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) ; CD80 antigen; CD80 molecule; CD80_MOUSE; Costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80.

Immunogen: KLH conjugated synthetic peptide derived from mouse B7-1/CD80:1-100/306

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: