B7-H4 Recombinant Protein | 90-369

B7-H4 Recombinant Protein | 90-369 | Gentaur UK, US & Europe Distribution

Tested Application: N/A

Application: This recombinant proteins is for research use only.

Tpredicted Molecular Weight: N/A

Physical State: Lyophilized

Buffer: Lyophilized from 0.2um-filtered solution in PBS. Reconstitute with 100 μl sterile water. Add 1X PBS to the desired protein concentration.

Storage Condition: Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.

Alternate Name: V-set Domain-containing T Cell Activation Inhibitor 1, VTCN1, B7h.5, Immune Costimulatory Protein B7-H4, T Cell Costimulatory Molecule B7x, Protein B7S1

Background: N/A

Shipping: N/A

Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

Source: CHO cells

Species: Human

By Source: CHO Cells

By Species: Human

Fusion Tag: Fc Tag

Sequence: The extracellular domain of human B7-H4 (aa 29-258) is fused to the N-terminus of the Fc region of human IgG1.

Bological Activity: Measured by the ablility to inhibit anti-CD3-induced proliferation of stimulated human T cells. Human T lymphocytes cultured for 72 hours with PHA were incubated for an additional 3 days in 96 well place coated with 500 ng/ml anti-CD3 and 10ug/ml human B7H4/Fc. The presence of human B7H4/Fc at 10ug/ml inhibited anti CD3 response by 30-50%. Optimal dilutions should be determined by each laboratory for each application.

Purity: >98% (SDS-PAGE).

Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).