Bakuchiol | 2494

Isolated from plant Psoralea corylifolia. Acts as an inhibitor of protein tyrosine phosphatase 1B (PTB1B (IC₅₀ = 20.8±1.9 µM). Antioxidant and an inhibitor of mitochondrial lipid peroxidation. Also inhibits inducible nitric oxide synthase (iNOS; NOS II) expression. DNA polymerase inhibitor. Shows antimicrobial and cytotoxic activity.

Bakuchiol is isolated from plant Psoralea corylifolia. Acts as an inhibitor of protein tyrosine phosphatase 1B (PTB1B (IC₅₀ = 20.8±1.9 µM). Antioxidant and an inhibitor of mitochondrial lipid peroxidation. Also inhibits inducible nitric oxide synthase (iNOS; NOS II) expression.

2494 | Bakuchiol DataSheet

Alternate Name/Synonyms: 4-(3-Ethenyl-3,7-dimethyl-1,6-octadienyl)phenol

Appearance: Yellow to brownish oil

Formulation: N/A

CAS Number: 10309-37-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₂₄O

Molecular Weight: 256.38

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO or EtOH

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent PTP1B and iNOS inhibitor

MDL Number: MFCD01707441

PubChem CID: 5468522

SMILES: CC(=CCCC(C)(C=C)C=CC1=CC=C(C=C1)O)C

InChi: InChI=1S/C18H24O/c1-5-18(4,13-6-7-15(2)3)14-12-16-8-10-17(19)11-9-16/h5,7-12,14,19H,1,6,13H2,2-4H3/b14-12+/t18-/m1/s1

InChi Key: LFYJSSARVMHQJB-QIXNEVBVSA-N