Description
BAX Monoclonal Antibody | E-AB-22128 | Gentaur UK, US & Europe Distribution
Type: Monoclonal Antibody
Synonyms: Apoptosis regulator BAX, BAX, Bax-protein, BAX, BAXA, Baxdelta2G9, Baxdelta2G9omega, Baxdelta2omega, Bcl-2-like protein 4, BCL2 associated X protein, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, Bcl2-L-4, BCL2L4, membrane isoform alpha
Application: WB, IHC-p
Reactivity: Human, Mouse, Rat
Host: Mouse
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Metabolism
Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic Peptide of Bax
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification Method: Protein A purification
Dilution: WB 1:1000-2000, IHC 1:100-200
Clone: Clone:1D8
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): 20 kDa