BAY 58-2667 (Free base) | 2452

A free base form of the nitric oxide (NO)- and heme-independent soluble guanylyl cyclase activator BAY 58-2667 hydrochloride (Cat. No. 2027).

BAY 58-2667 is a nitric oxide (NO)- and heme-independent soluble guanylyl cyclase activator. Displays potent cardiovascular effects. Improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure. Exhibits potent vasodilator and antiplatelet activity.

2452 | BAY 58-2667 (Free base) DataSheet

Alternate Name/Synonyms: 4-((4-carboxybutyl)(2-((4-phenethylbenzol)- oxy)phenethyl)amino)methyl(benzoic) acid; BAY582667; cinaciguat

Appearance: White solid

Formulation: N/A

CAS Number: 329773-35-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₆H₃₉NO₅

Molecular Weight: 565.7

Cell-Permeable?: Yes

Purity: ≥98% by NMR

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A guanylyl cyclase activator

MDL Number: N/A

PubChem CID: 9808022

SMILES: C1=CC=C(C=C1)CCC2=CC=C(C=C2)COC3=CC=CC=C3CCN(CCCCC(=O)O)CC4=CC=C(C=C4)C(=O)O

InChi: InChI=1S/C36H39NO5/c38-35(39)12-6-7-24-37(26-30-19-21-33(22-20-30)36(40)41)25-23-32-10-4-5-11-34(32)42-27-31-17-15-29(16-18-31)14-13-28-8-2-1-3-9-28/h1-5,8-11,15-22H,6-7,12-14,23-27H2,(H,38,39)(H,40,41)

InChi Key: WPYWMXNXEZFMAK-UHFFFAOYSA-N