Description
A L-type Ca²⁺-channel activator (EC₅₀ = 17.3 nM). In combination with BIX01294 (Cat. No. 1678-5, 25), enables reprogramming of Oct4/Klf4-transduced mouse embryonic fibroblasts.
(+-)-Bay K 8644 is a L-type Ca²⁺-channel activator (EC₅₀ = 17.3 nM). In combination with BIX01294 (Cat. No. 1678-5, 25), enables reprogramming of Oct4/Klf4-transduced mouse embryonic fibroblasts.
1682 | (+-)-Bay K 8644 DataSheet
Alternate Name/Synonyms: 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl) phenyl]-3-pyridinecarboxylic acid, methyl ester
Appearance: Yellow solid
Formulation: N/A
CAS Number: 71145-03-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₅F₃N₂O₄
Molecular Weight: 356.3
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (100 mM) and Ethanol (100 mM)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A L-type Ca²⁺-channel activato
MDL Number: MFCD00036697
PubChem CID: 2303
SMILES: CC1=C(C(C(=C(N1)C)[N+](=O)[O-])C2=CC=CC=C2C(F)(F)F)C(=O)OC
InChi: InChI=1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3
InChi Key: ZFLWDHHVRRZMEI-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |