BCAP29 polyclonal Antibody | BS8141

BCAP29 polyclonal Antibody | BS8141 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: BAP29 (BCR-associated protein 29), also known as BCAP29 (B-cell receptor-associated protein 29), is a multi-pass membrane protein localizing to the endoplasmic reticulum (ER) and belonging to the BCAP29/BCAP31 family of proteins. It is ubiquitously expressed with predominant expression in brain and testis. BAP29 contains a hydrophobic N-terminus, three transmembrane domains, a coiled-coil region and a C-terminal double-lysine motif that is implicated in vesicular transport. BAP29 exists as a homodimer or as a heterodimer with BAP31 and plays a role in membrane IgD molecule retention in the ER. In addition, the BAP29/BAP31 complex functions as a cargo receptor for MHC class I molecules and is important for recruiting the class I molecules to exit sites of the ER. The BAP29/BAP31 complex is also essential for proper trafficking from the ER to the Golgi.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: BCAP29 polyclonal Antibody detects endogenous levels of BCAP29 protein.

Molecular Weight: ~ 28 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: B-cell receptor-associated protein 29; BCR-associated protein 29; Bap29; BCAP29; BAP29

Immunogen: Recombinant full length Human BCAP29.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: