BCL-6 Antibody| F40298-0.4ML

BCL-6 Antibody| F40298-0.4ML | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Format: Purified

Clone: 305CT16.3.3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG1, k

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:100-1:250

Application Note: Titration of the BCL-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This BCL-6 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 676-704 from the human protein was used as the immunogen for this BCL-6 antibody.

Storage: Aliquot the BCL-6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A