Additional Information
Size: |
100 µl |
Target: |
Bcl-xL (pSer62) |
Conjugate: |
Dylight 488 |
Research Area: |
Cancer | Apoptosis | Intracellular | Bcl2 Family | Cancer | Invasion/microenvironment | Cancer | Cancer Metabolism |
Alternative Name: |
Bcl-xL Antibody, B-cell lymphoma-extra large (Bcl-xL) Antibody, Bcl-x Antibody, Apoptosis regulator Bcl-X Antibody, B cell lymphoma 2 like Antibody, PPP1R52 Antibody, Bcl xL Antibody, DKFZp781P2092 Antibody, BclXs Antibody, Apoptosis regulator Bcl X |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic phospho-peptide from human Bcl-xL around the phosphorylation site of serine 62 (pSer62). |
Immunogen Species: |
Human |
Applications: |
WB, IHC, ELISA |
Host: |
Rabbit |
Isotype: |
N/A |
Species Reactivity: |
Human, Mouse, Rat |
Antibody Dilution: |
WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide |
Concentration: |
N/A |
Specificity: |
Detects endogenous levels of Bcl-xL protein only when phosphorylated at serine 62 (pSer62). Detects a band at ~26 kDa. |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
N/A |
Cellular Localization: |
Mitochondrion Inner Membrane, Mitochondrion Outer Membrane, Mitochondrion Matrix, Cytosol, Nucleus Membrane, Single-Pass Membrane Protein, Cytoplasmic Side, Cytoskeleton, Centrosome, Synaptic Vesicle Membrane, Endoplasmic Reticulum, Mitochondrion, Nu |
Tissue Specificity: |
Bcl-xL(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-xL(L) is found in tissues containing long-lived postmitotic cells, such as adult brain. |
Accession Number: |
NP_001182.1 |
Gene ID: |
598 |
Swiss-Prot: |
Q07817 |
Field of Use: |
For in vitro research use only. |