Bempedoic acid | B1913

Bempedoic acid is an ATP citrate lyase (ACL) inhibitor. ACL is an enzyme involved in fatty acid and cholesterol synthesis. Bempedoic acid is a convenient, oral, once-daily LDL-C lowering drug that significantly reduces elevated LDL-C levels in patients with hypercholesterolemia, including patients inadequately treated with current lipid-modifying therapies. Bempedoic acid, a novel, non-statin, targeted therapy, works in the liver to block cholesterol biosynthesis.

Bempedoic acid is an ATP citrate lyase (ACL) inhibitor. ACL is an enzyme involved in fatty acid and cholesterol synthesis. Bempedoic acid is a convenient, oral, once-daily LDL-C lowering drug that significantly reduces elevated LDL-C levels in patients with hypercholesterolemia, including patients inadequately treated with current lipid-modifying therapies. Bempedoic acid, a novel, non-statin, targeted therapy, works in the liver to block cholesterol biosynthesis.

B1913 | Bempedoic acid DataSheet

Alternate Name/Synonyms: 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid; ETC-1002; ESP-55016

Appearance: Light yellow to yellow liquid

Formulation: N/A

CAS Number: 738606-46-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₃₆O₅

Molecular Weight: 344.49

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An ATP citrate lyase (ACL) inhibitor

MDL Number: N/A

PubChem CID: 10472693

SMILES: CC(C)(CCCCCC(CCCCCC(C)(C)C(=O)O)O)C(=O)O

InChi: InChI=1S/C19H36O5/c1-18(2,16(21)22)13-9-5-7-11-15(20)12-8-6-10-14-19(3,4)17(23)24/h15,20H,5-14H2,1-4H3,(H,21,22)(H,23,24)

InChi Key: HYHMLYSLQUKXKP-UHFFFAOYSA-N