26
Bendamustine Hydrochloride | B1596
- SKU:
- 26-B1596-GEN
- Availability:
- Usually shipped in 5 working days
Description
Bendamustine is a novel alkylating agent with a benzimidazole ring giving it purine analogue-like properties. Like other alkylating agents, bendamustine is thought to act by modifying and cross linking purine bases in DNA, thus inhibiting DNA, RNA and protein synthesis and leading to cell death in rapidly dividing cells. Bendamustine appears to have a special activity against B cell leukemias and lymphomas.
Bendamustine is a novel alkylating agent with a benzimidazole ring giving it purine analogue-like properties. Like other alkylating agents, bendamustine is thought to act by modifying and cross linking purine bases in DNA, thus inhibiting DNA, RNA and protein synthesis and leading to cell death in rapidly dividing cells. Bendamustine appears to have a special activity against B cell leukemias and lymphomas.
B1596 | Bendamustine Hydrochloride DataSheet
Alternate Name/Synonyms: 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride
Appearance: White solid
Formulation: N/A
CAS Number: 3543-75-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₆H₂₁Cl₂N₃O₂.HCl
Molecular Weight: 394.71
Cell-Permeable?: Yes
Purity: ≥98%
Solubilities: DMSO (>30 mg/ml) or EtOH (>20 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: An anticancer agent
MDL Number: MFCD16879055
PubChem CID: 77082
SMILES: CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl
InChi: InChI=1S/C16H21Cl2N3O2.ClH/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23;/h5-6,11H,2-4,7-10H2,1H3,(H,22,23);1H
InChi Key: ZHSKUOZOLHMKEA-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |