26
Beta-Secretase Inhibitor II | 7502
- SKU:
- 26-7502-GEN
- Availability:
- Usually shipped in 5 working days
Description
A potent, cell permeable and reversible inhibitor of β-secretase that corresponds to the β-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Aβtotal (IC₅₀ = 700 nM) and Aβ1-42 (IC₅₀ = 2.5 µM) in CHO cells stably transfected with wild-type APP751.
7502 | Beta-Secretase Inhibitor II DataSheet
Alternate Name/Synonyms:
Appearance: White solid
Formulation: N/A
CAS Number: N/A
Structure Available?: No
Peptide sequence: Z-Val-Leu-Leu--CHO
Salt Form: No
Molecular Formula: C₂₅H₃₉N₃O₅
Molecular Weight: 461.6
Cell-Permeable?: Yes
Purity: ≥95% by HPLC
Solubilities: DMSO
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A beta-secretase inhibitor
MDL Number: N/A
PubChem CID: 10253763
SMILES: CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(C(C)C)NC(=O)OCC1=CC=CC=C1
InChi: 239-200(315)150(93-258)251-190(305)143(82-112-90-215-95-219-112)248-203
InChi Key: YHUAFMGVVANYBT-FKBYEOEOSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |