BI-7273 | B1879

BI-7273 is a potent, selective, and cell-permeable BRD9 bromodomain inhibitor (IC₅₀ ~19 nM). It displays high selectivity against the other bromodomain family members (48 bromodomains) and kinases.

BI-7273 is a potent, selective, and cell-permeable BRD9 bromodomain inhibitor (IC₅₀ ~19 nM). It displays high selectivity against the other bromodomain family members (48 bromodomains) and kinases.

B1879 | BI-7273 DataSheet

Alternate Name/Synonyms: 4-(4-((dimethylamino)methyl)-3,5-dimethoxyphenyl)-2-methyl-2,7-naphthyridin-1(2H)-one

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1883429-21-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₃N₃O₃

Molecular Weight: 353.41

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, selective, and cell-permeable BRD9 bromodomain inhibitor

MDL Number: N/A

PubChem CID: 118796358

SMILES: CN1C=C(C2=C(C1=O)C=NC=C2)C3=CC(=C(C(=C3)OC)CN(C)C)OC

InChi: InChI=1S/C20H23N3O3/c1-22(2)11-17-18(25-4)8-13(9-19(17)26-5)16-12-23(3)20(24)15-10-21-7-6-14(15)16/h6-10,12H,11H2,1-5H3

InChi Key: RBUYFHLQNPJMQM-UHFFFAOYSA-N