Biotin-HPDP | 2329

KEY FEATURES: • HPDP contains a dithiopyridyl group which is reactive towards sulfhydryl groups (-SH) such as in cysteine (C) side chain to form stable disulfide bond • Contains a spacer arm with a length of 29.2 Å that prevents steric hindrance to biotin labeling • The spacer is cleavable at the disulfide bond with reducing agent, such as DTT, TCEP, etc. • Must be dissolved in an organic solvent such as DMF or DMSO before dilution with aqueous buffers APPLICATIONS: • Ideal for biotinylating antibody or protein for use in protein detection, purification or immobilization

Biotin-HPDP is a sulfhydryl reactive biotinylation reagent

2329 | Biotin-HPDP DataSheet

Alternate Name/Synonyms: N-[6-(Biotinamido)hexyl]-3’-(2’-pyridyldithio)-propionamide; Biotin-HPDP, pyridyldithiol-biotin, pyridyldisulfide-biotin

Appearance: White to Off-white Solid

Formulation: N/A

CAS Number: 129179-83-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₃₇N₅O₃S₃

Molecular Weight: 539.78

Cell-Permeable?: No

Purity: ≥90% by NMR

Solubilities: DMSO or DMF

Handling: Protect from moisture

Country of Origin: USA

Tag Line: A sulfhydryl reactive biotinylation reagent

MDL Number: MFCD00867240

PubChem CID: 46783562

SMILES: C1C2C(C(S1)CCCCC(=O)NCCCCCCNC(=O)CCSSC3=CC=CC=N3)NC(=O)N2

InChi: InChI=1S/C24H37N5O3S3/c30-20(10-4-3-9-19-23-18(17-33-19)28-24(32)29-23)25-13-6-1-2-7-14-26-21(31)12-16-34-35-22-11-5-8-15-27-22/h5,8,11,15,18-19,23H,1-4,6-7,9-10,12-14,16-17H2,(H,25,30)(H,26,31)(H2,28,29,32)/t18?,19-,23?/m0/s1

InChi Key: QLPHBNRMJLFRGO-KPRXVCGWSA-N