Biotin-LC-LC-NHS | 2346

Biotin-LC-LC-NHS is a useful reagent for biotinylation of primary amines under mild conditions (pH~6.5-8.5). Some examples of primary amines for biotinylation include lysines on the surface of proteins, antibodies, etc. Inserts a 14-atom spacer between biotin and the target ligand, thus minimizing the steric hindrance in binding avidin or streptavidin to some biotinylated compounds and increase sensitivity for detection.

Biotin-LC-LC-NHS is a useful reagent for biotinylation of primary amines under mild conditions (pH~6.5-8.5).

2346 | Biotin-LC-LC-NHS DataSheet

Alternate Name/Synonyms: 6-((6-((Biotinoyl)amino)hexanoyl)amino)hexanoic acid, succinimidyl ester; Biotin-XX-NHS

Appearance: White solid

Formulation: N/A

CAS Number: 89889-52-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₆H₄₁NO₇S

Molecular Weight: 567.7

Cell-Permeable?: No

Purity: ≥95% by HPLC

Solubilities: DMF (~ 25 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A biotinylation agent for primary amines

MDL Number: MFCD00467154

PubChem CID: 16219024

SMILES: C1CC(=O)N(C1=O)OC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCC2C3C(CS2)NC(=O)N3

InChi: InChI=1S/C26H41N5O7S/c32-20(27-16-8-2-4-12-24(36)38-31-22(34)13-14-23(31)35)10-3-1-7-15-28-21(33)11-6-5-9-19-25-18(17-39-19)29-26(37)30-25/h18-19,25H,1-17H2,(H,27,32)(H,28,33)(H2,29,30,37)/t18-,19-,25-/m0/s1

InChi Key: ATYCFNRXENKXSE-MHPIHPPYSA-N