Sulfo-NHS-LC-Biotin | 2326

KEY FEATURES: • Amine-reactive; has a spacer with arm length of 22.4 Å which helps to minimize steric hindrance to biotin labeling • More water-soluble than the corresponding NHS compound without the sulfo group • Membrane-impermeable • Forms permanent amide bonds and the spacer arm cannot be cleaved APPLICATIONS: • Sulfo-NHS-LC-Biotin is ideal for biotinylating antibody or protein that can then be used for protein detection, purification or immobilization • Sulfo-NHS-LC-Biotin is particularly useful for targeting cell surface proteins due to the membrane-impermeability of this reagent

Sulfo-NHS-LC-Biotin is a water-soluble protein biotinylation reagent.

2326 | Sulfo-NHS-LC-Biotin DataSheet

Alternate Name/Synonyms: Sulfosuccinimidyl 6-(biotinamido) Hexanoate; Biotinamidohexanoic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt

Appearance: White to Off-white Solid

Formulation: N/A

CAS Number: 127062-22-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₁₈O₈N₃S₂Na

Molecular Weight: 556.59

Cell-Permeable?: No

Purity: ≥90% by NMR

Solubilities: H₂O (~ 20 mg/ml)

Handling: Protect from moisture

Country of Origin: USA

Tag Line: Sulfo-NHS-LC-Biotin is a water-soluble protein biotinylation reagent.

MDL Number: MFCD00078534

PubChem CID: 16219001

SMILES: O=C([MH]1)NC2C1CSC2CCCCC(NCCCCCC(ON3C(C(S(=O)(O[Na])=O)CC3=O)=O)=O)=O

InChi: InChI=1S/C20H30N4O9S2.Na/c25-15(7-4-3-6-13-18-12(11-34-13)22-20(29)23-18)21-9-5-1-2-8-17(27)33-24-16(26)10-14(19(24)28)35(30,31)32;/h12-14,18H,1-11H2,(H,21,25)(H2,22,23,29)(H,30,31,32);

InChi Key: RDSJVNGBJUJRRW-UHFFFAOYSA-N