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Biotin-VDVAD-FMK | 1032

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SKU:
26-1032-GEN
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£1,334.00

Description

This is a synthetic peptide that irreversibly inhibits caspase-2 and related caspase activity. It is a biotinylated derivative of the Caspase-2 inhibitor Z-VDVAD-FMK (Cat # 1142). This conjugation with biotin allows detection of activated caspases in conjunction with avidin-tags. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Biotin-VDVAD-FMK is a biotinylated derivative of the Caspase-2 inhibitor Z-VDVAD-FMK (Cat # 1142).

1032 | Biotin-VDVAD-FMK DataSheet

Alternate Name/Synonyms: Biotin-VDVAD-FMK, VDVAD-FMK, Biotin

Appearance: Liquid

Formulation: DMSO (10 mM)

CAS Number: N/A

Structure Available?: No

Peptide sequence: Biotin-Val-Asp(OMe)-Val-Ala-Asp(OMe)-FMK

Salt Form: No

Molecular Formula: C₄₀H₆₅FN₈O₁₂S

Molecular Weight: 901.05

Cell-Permeable?: Yes

Purity: Single spot by TLC

Solubilities: N/A

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A Caspase-2 inhibitor

MDL Number: N/A

PubChem CID: N/A

SMILES: O=C(OC)C[C@H](NC([C@@H](NC(C(C(C)C)NC([C@@H](NC(C(C(C)C)NC(CCCCCNC(CCCC[C@H]1SC[C@](N2)([H])[C@@]1([H])NC2=O)=O)=O)=O)CC(OC)=O)=O)=O)C)=O)C(CF)=O

InChi: InChI=1S/C40H65FN8O12S/c1-21(2)33(47-30(52)15-9-8-12-16-42-29(51)14-11-10-13-28-35-26(20-62-28)46-40(59)49-35)39(58)45-25(18-32(54)61-7)37(56)48-34(22(3)4)38(57)43-23(5)36(55)44-24(27(50)19-41)17-31(53)60-6/h21-26,28,33-35H,8-20H2,1-7H3,(H,42,51)(H,43,57)(H,44,55)(H,45,58)(H,47,52)(H,48,56)(H2,46,49,59)/t23-,24-,25-,26+,28+,33?,34?,35+/m0/s1

InChi Key: HZMQEZLCGJXARR-LFJGSYRESA-N

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Additional Information

Storage Condition:
-20°C
Shipping Condition:
Gel Pack
Shelf Life:
12 months
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