Description
A biotinylated derivative of the tetrapeptide inhibitor ASTD-FMK, which acts as a competitive inhibitor for the cleavage site of pro-EMAP II (Endothelial monocyte-activating polypeptide). EMAPII, which is a proinflammatory cytokine and a chemoattractant for monocytes, is specifically processed and released upon the induction of apoptosis in cultured cells.
Biotinyl-ASTD-FMK is a biotinylated derivative of the tetrapeptide inhibitor ASTD-FMK, which acts as a competitive inhibitor for the cleavage site of pro-EMAP II (Endothelial monocyte-activating polypeptide). EMAPII, which is a proinflammatory cytokine and a chemoattractant for monocytes, is specifically processed and released upon the induction of apoptosis in cultured cells.
1985 | Biotinyl-ASTD-FMK DataSheet
Alternate Name/Synonyms: Biotinyl-Ala-Ser-Thr-DL-Asp-Fluoromethylketone; Biotinyl-ASTD-Fluoromethylketone
Appearance: Yellow solid
Formulation: N/A
CAS Number: N/A
Structure Available?: Yes
Peptide sequence: Biotinyl-ASTD-FMK
Salt Form: No
Molecular Formula: C₂₅H₃₉FN₆O₁₀S
Molecular Weight: 634.68
Cell-Permeable?: No
Purity: ≥95% by HPLC
Solubilities: DMSO
Handling: Protect from light and mositure
Country of Origin: USA
Tag Line: An EMAP II inhibitor
MDL Number: N/A
PubChem CID: N/A
SMILES: N/A
InChi: N/A
InChi Key: N/A
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
60 months |