Bioymifi | 9424

Bioymifi is a potent and selective death receptor 5 (DR5) activator. Bioymifi works by mimicking the ability of TRAIL, the natural DR5 ligand, to stimulate clustering of DR5, triggering apoptosis. Bioymifi caused apoptosis and cell death in a variety of human cancer cell lines including T98G human glioblastoma cells, lung cancer cell lines H460 and H1155, the cervical cancer cell line HeLa, the osteosarcoma cell line U2OS, the pancreatic carcinoma cell line Miapaca and the colon cancer cell line HT29.

Bioymifi is a potent and selective death receptor 5 (DR5) activator. Bioymifi works by mimicking the ability of TRAIL, the natural DR5 ligand, to stimulate clustering of DR5, triggering apoptosis. Bioymifi caused apoptosis and cell death in a variety of human cancer cell lines including T98G human glioblastoma cells, lung cancer cell lines H460 and H1155, the cervical cancer cell line HeLa, the osteosarcoma cell line U2OS, the pancreatic carcinoma cell line Miapaca and the colon cancer cell line HT29.

9424 | Bioymifi DataSheet

Alternate Name/Synonyms: (Z)-5-(5-[(3-[4-Bromophenyl]-2-imino-4-oxothiazolidin-5-ylidene)methyl]furan-2-yl)isoindoline-1,3-dione

Appearance: Orange to dark orange solid

Formulation: N/A

CAS Number: 1420071-30-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₁₂BrN₃O₄S

Molecular Weight: 494.32

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 2 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective death receptor 5 (DR5) activator

MDL Number: N/A

PubChem CID: 70678419

SMILES: C1=CC(=CC=C1N2C(=O)C(=CC3=CC=C(O3)C4=CC5=C(C=C4)C(=O)NC5=O)SC2=N)Br

InChi: InChI=1S/C22H12BrN3O4S/c23-12-2-4-13(5-3-12)26-21(29)18(31-22(26)24)10-14-6-8-17(30-14)11-1-7-15-16(9-11)20(28)25-19(15)27/h1-10,24H,(H,25,27,28)/b18-10-,24-22?

InChi Key: ULBOWKXOFOTCMU-NLDKGBHCSA-N