Bloom Syndrome (phospho Ser527) Antibody | 39-856

Bloom Syndrome (phospho Ser527) Antibody | 39-856 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat, Non-Human Primate

Homology: N/A

Immunogen: A synthetic peptide surrounding amino acid S527

Research Area: Phospho-Specific

Tested Application: E, WB, IHC

Application: ELISA, Western (immuno) blotting, Immunostaining (in testing)

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Affinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: N/A

Concentration: N/A

Storage Condition: N/A

Alternate Name: Bloom Syndrome Protein pS527 phospho specific, BS, RECQ2, RECQL2, RECQL3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids; including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes.