Description
Bloom Syndrome (phospho Ser527) Antibody | 39-856 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat, Non-Human Primate
Homology: N/A
Immunogen: A synthetic peptide surrounding amino acid S527
Research Area: Phospho-Specific
Tested Application: E, WB, IHC
Application: ELISA, Western (immuno) blotting, Immunostaining (in testing)
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Affinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: N/A
Concentration: N/A
Storage Condition: N/A
Alternate Name: Bloom Syndrome Protein pS527 phospho specific, BS, RECQ2, RECQL2, RECQL3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids; including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes.