BMP-2, Human Recombinant | 4577

BMPs (bone morphogenetic proteins) belong to the TGF- superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-2 also plays an important role in cardiac morphogenesis. BMP-2 is expressed in a variety of tissues such as lung, spleen, brain, liver, prostate ovary, and small intestine. Recombinant human BMP-2 is a 26 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains

4577 | BMP-2 human recombinant DataSheet

Biomolecule/Target: BMP-2

Synonyms: BMP-2, BMP2A, bone morphogenetic protein2

Alternates names: -defensin 1, BD-1, Defensin 1, hBD-1, HBD1, HBP1, DEFB1, HBD-1, HBP-1, DEFB101, DEFB-1, MGC51822

Taglines: A protein involved in the hedgehog and TGF beta signaling pathway

NCBI Gene ID #: 1672

NCBI Gene Symbol: DEFB1

Gene Source: Human

Accession #: P60022

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 0.1-1 µg/ml.

Results: < 50 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 5.0 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized without additives

Reconstitution Instructions: Reconstitute in dHO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A