BW
BMP-5 (L163) polyclonal Antibody | BS3455
- SKU:
- BW-BS3455
- Availability:
- Usually ships in 5 working days
Description
BMP-5 (L163) polyclonal Antibody | BS3455 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFβ receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: BMP-5 (L163) polyclonal Antibody detects endogenous levels of BMP-5 protein.
Molecular Weight: ~ 52 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Bone morphogenetic protein 5; BMP 5; BMP5
Immunogen: Synthetic peptide, corresponding to amino acids 130-180 of Human BMP-5.
Conjugate: N/A
Modification: N/A
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: N/A