Description
BMS-779788 is a LXR partial agonist with IC₅₀ values of 68 nM for LXRα and 14 nM for LXRβ. BMS-779788 induces LXR target genes in blood in vivo with an EC₅₀ = 610 nM, a value similar to its in vitro blood gene induction potency.
BMS-779788 is a LXR partial agonist with IC₅₀ values of 68 nM for LXRα and 14 nM for LXRβ. BMS-779788 induces LXR target genes in blood in vivo with an EC₅₀ = 610 nM, a value similar to its in vitro blood gene induction potency.
Alternate Name/Synonyms: 2-(2-(2-(2-chlorophenyl)propan-2-yl)-1-(3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)-1H-imidazol-4-yl)propan-2-ol, BMS 779788, EXEL04286652, XL652, BMS779788, EXEL-04286652, XL-652
Appearance: White to off-white solid
Formulation:
CAS Number: 918348-67-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₈H₂₉ClN₂O₃S
Molecular Weight: 509.06
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent partial LXR agonist
MDL Number:
PubChem CID: 59251511
SMILES: CC(C)(C1=CC=CC=C1Cl)C2=NC(=CN2C3=CC=C(C=C3)C4=CC(=CC=C4)S(=O)(=O)C)C(C)(C)O
InChi: InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(2
InChi Key: JLPURTXCSILYLW-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |