BNIP3 Antibody | 19-791

BNIP3 Antibody | 19-791 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human BNIP3 (NP_004043.3) .

Research Area: Apoptosis, Autophagy, Cancer, Cell Cycle

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: MCF7

Positive Control 2: NCI-H460

Positive Control 3: Jurkat

Positive Control 4: SH-SY5Y

Positive Control 5: Mouse kidney

Positive Control 6: Mouse heart

Molecular Weight: Observed: 22-70kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.