Boc-D-FMK | 1160

A synthetic peptide that irreversibly inhibits activity of caspase family proteases and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Boc-D-FMK is a cell-permeable, irreversible inhibitor of caspase family proteases and blocks apoptosis

1160 | Boc-D-FMK DataSheet

Alternate Name/Synonyms: Boc-D-FMK, Boc-D-fluoromethylketone, Caspase Inhibitor (fluoromethylketone)

Appearance: Lyophilized solid

Formulation: N/A

CAS Number: N/A

Structure Available?: No

Peptide sequence: Boc-Asp(OMe)-FMK

Salt Form: No

Molecular Formula: C₁₁H₁₈FNO₅

Molecular Weight: 263.26

Cell-Permeable?: Yes

Purity: >95% by HPLC

Solubilities: DMSO (20 mM)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A caspase family inhibitor

MDL Number: MFCD03453073

PubChem CID: 16760348

SMILES: CC(C)(C)OC(=O)NC(CC(=O)OC)C(=O)CF

InChi: InChI=1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)

InChi Key: MXOOUCRHWJYCAL-UHFFFAOYSA-N