Description
A bisperoxovanadium compound that acts as a potent protein phosphotyrosine phosphatase (PTP) inhibitor as well as an insulin receptor kinase (IRK) activator. Also an excellent insulin mimetic in vitro and in vivo and a potent PTEN inhibitor (IC₅₀ = 38 nM).
bpV(phen) is a bisperoxovanadium compound that acts as a potent protein phosphotyrosine phosphatase (PTP) inhibitor as well as an insulin receptor kinase (IRK) activator. Also an excellent insulin mimetic in vitro and in vivo and a potent PTEN inhibitor (IC₅₀ = 38 nM).
Alternate Name/Synonyms: Potassium bisperoxo(1,10-phenanthroline)oxovanadate (V)
Appearance: Yellow to orange solid
Formulation: N/A
CAS Number: 42494-73-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: K[VO(O₂)₂C₁₂H₈N₂].3H₂O
Molecular Weight: 404.3
Cell-Permeable?: No
Purity: ≥98% by ⁵¹V-NMR
Solubilities: DMSO or H₂O
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A PTP and PTEN inhibitor
MDL Number: N/A
PubChem CID: 16760322
SMILES: C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1.O.O.O.[OH-].OO.OO.[K+].[V]
InChi: InChI=1S/C12H8N2.K.2H2O2.4H2O.V/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;;2*1-2;;;;;/h1-8H;;2*1-2H;4*1H2;/q;+1;;;;;;;/p-1
InChi Key: GZEXWPZCNNQQRZ-UHFFFAOYSA-M
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
48 months |