BRD7116 | B1578

BRD 7116 is a selective inhibitor of leukemia stem cell (LSC) activity (EC₅₀ value of 200 nM). BRD 7116 does not affect normal hematopoietic stem cells or AML cell lines (EC₅₀s = 20 µM).

BRD 7116 is a selective inhibitor of leukemia stem cell (LSC) activity (EC₅₀ value of 200 nM). BRD 7116 does not affect normal hematopoietic stem cells or AML cell lines (EC₅₀s = 20 µM).

B1578 | BRD7116 DataSheet

Alternate Name/Synonyms: N,N'-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]

Appearance: White solid

Formulation: N/A

CAS Number: 329059-55-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₈H₃₆N₂O₄S

Molecular Weight: 496.66

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>40 mg/ml) or EtOH (>10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A leukemia stem cell (LSC) inhibitor

MDL Number: MFCD02168947

PubChem CID: 981129

SMILES: CC1(C(C1(C)C)C(=O)NC2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)C4C(C4(C)C)(C)C)C

InChi: InChI=1S/C28H36N2O4S/c1-25(2)21(26(25,3)4)23(31)29-17-9-13-19(14-10-17)35(33,34)20-15-11-18(12-16-20)30-24(32)22-27(5,6)28(22,7)8/h9-16,21-22H,1-8H3,(H,29,31)(H,30,32)

InChi Key: UHXFWAHRAMUDLJ-UHFFFAOYSA-N