Description
BRD 7116 is a selective inhibitor of leukemia stem cell (LSC) activity (EC₅₀ value of 200 nM). BRD 7116 does not affect normal hematopoietic stem cells or AML cell lines (EC₅₀s = 20 µM).
BRD 7116 is a selective inhibitor of leukemia stem cell (LSC) activity (EC₅₀ value of 200 nM). BRD 7116 does not affect normal hematopoietic stem cells or AML cell lines (EC₅₀s = 20 µM).
Alternate Name/Synonyms: N,N'-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]
Appearance: White solid
Formulation: N/A
CAS Number: 329059-55-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₈H₃₆N₂O₄S
Molecular Weight: 496.66
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>40 mg/ml) or EtOH (>10 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A leukemia stem cell (LSC) inhibitor
MDL Number: MFCD02168947
PubChem CID: 981129
SMILES: CC1(C(C1(C)C)C(=O)NC2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)C4C(C4(C)C)(C)C)C
InChi: InChI=1S/C28H36N2O4S/c1-25(2)21(26(25,3)4)23(31)29-17-9-13-19(14-10-17)35(33,34)20-15-11-18(12-16-20)30-24(32)22-27(5,6)28(22,7)8/h9-16,21-22H,1-8H3,(H,29,31)(H,30,32)
InChi Key: UHXFWAHRAMUDLJ-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |