Description
Bu-1a Antibody [21-1A4] (FITC) | 99-291 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Chicken
Homology: N/A
Immunogen: Bursa cells from one-day-old H.B15 (Bu-1a/b) strain chickens
Research Area: Other
Tested Application: IHC-Fr, ICC, Flow, IP
Application: Bu-1a Antibody [21-1A4] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
Specificiy: Bu-1a
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [21-1A4]
Isotype: IgG1
Conjugate: FITC
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: ChB6.1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Chicken Bu-1a, a product of the Bu-1a allele, is expressed on the cell surface as a disulfide-linked homodimer. In 10-week-old H.B15 and H.B2 chickens, Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes. In chickens heterozygous for the Bu-1 alleles (Bu-1a/b) , Bu-1a does not exhibit allelic exclusion. The monoclonal antibody 21-1A4 does not react with cells from CHA and H.B14ab strains by immunofluorescence.