c-Fos polyclonal Antibody | BS90295

c-Fos polyclonal Antibody | BS90295 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB FC

Application Range: WB:1:1,000 FC:1:50-1:100

Background: The c-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phospho-protein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. Functional homologs of c-Fos include the Fra-1, Fra-2 and Fos B genes. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: c-Fos polyclonal Antibody detects endogenous levels of c-Fos protein.

Molecular Weight: 62 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FOS, Activator protein 1, AP 1, C FOS, Cellular oncogene c fos, Cellular oncogene fos, FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS), FBJ murine osteosarcoma viral oncogene homolog, FBJ murine osteosarcoma viral v fos oncogene homolog, FBJ Osteosarcoma Virus, FOS, FOS protein, FOS, G0 G1 switch regulatory protein 7, G0/G1 switch regulatory protein 7, G0S7, Oncogene FOS, p55, proto oncogene c Fos, Proto oncogene protein c fos, Proto-oncogene c-Fos, v fos FBJ murine osteosarcoma viral oncogene homolog,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: