Description
c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins, and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. The MAP kinase homologue, JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activate c-Jun.
3009 | c-Jun antibody DataSheet
Antibody Target: c-Jun
Target Alternative Name: JUN , AP1 , p39 , c-Jun
Tag Line:
Category: c-jun
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human
Immunogen Sequence: E. coli-expressed recombinant human c-Jun fusion protein
Accession #: P05412
Gene ID: 3725
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.
Purification: Affinity purified
Application: Western blot
Positive Control: Recombinant human c-Jun (Cat.# 7001-100)
Application And Usages: The antibody can be used in Western Blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human c-Jun (Cat.# 7001-100) can be used as a positive control.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified: Not Verified
Flow Cytometry Verified: Not Verified
Additional Information
Size: |
30 ug |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |