400

c-Met Antibody (pTyr1349)

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SKU:
400-SPC-1401D-GEN
Availability:
IN STOCK
£1,198.00

Description

Rabbit Anti-Human c-Met (pTyr1349) Polyclonal

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Additional Information

Size:
100 µl
Target:
c-Met (pTyr1349)
Conjugate:
Unconjugated
Research Area:
Cell Signaling | Protein Phosphorylation | Tyrosine Kinases | Receptor Tyrosine Kinases | Cancer | Tumor Biomarkers | Oncoproteins | Growth Factor Receptors | Cell Signaling | Epigenetics and Nuclear Signaling | Transcription
Alternative Name:
MET Antibody, Proto-oncogene c-Met Antibody, Met proto-oncogene (hepatocyte growth factor receptor) Antibody, HGF/SF receptor Antibody, AUTS9 Antibody, D249 Antibody, Oncogene MET Antibody, Met protooncogene Antibody, Par4 Antibody, MET proto oncogen
Category:
Antibodies
Product Type:
Polyclonal Antibody
Immunogen:
Synthetic phospho-peptide from human c-Met around the phosphorylation site of tyrosine 1349 (pTyr1349).
Immunogen Species:
Human
Applications:
WB
Host:
Rabbit
Isotype:
IgG
Species Reactivity:
Human, Mouse, Rat
Antibody Dilution:
WB (1:250-1:1000); optimal dilutions for assays should be determined by the user.
Purification:
Peptide Affinity Purified
Storage Buffer:
PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Concentration:
N/A
Specificity:
Detects endogenous levels of c-Met only when phosphorylated at tyrosine 1349 (pTyr1349). Detects a band at ~145 kDa.
Storage:
-20ºC
Shipping:
Blue Ice or 4ºC
Certificate of Analysis:
N/A
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein, Secreted, Extracellular Region, Plasma Membrane, Basal Plasma Membrane, Integral Component Of Plasma Membrane, Cell Surface, Integral Component Of Membrane, Intracellular
Tissue Specificity:
Expressed in normal hepatocytes as well as in epithelial cells lining the stomach, the small and the large intestine. Found also in basal keratinocytes of esophagus and skin. High levels are found in liver, gastrointestinal tract, thyroid and kidney.
Accession Number:
NP_000236.2
Gene ID:
4233
Swiss-Prot:
P08581
Field of Use:
For in vitro research use only.
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