c-Myc (c-Myc ) monoclonal Antibody | MB62860

c-Myc (c-Myc ) monoclonal Antibody | MB62860 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IF, IHC, WB

Application Range: WB 1:50~100, IHC 1:50, IF 1:100

Background: c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: v-myc avian myelocytomatosis viral oncogene homolog

Molecular Weight: 50.4 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: bHLHe39; c-Myc; MRTL; MYCC

Immunogen: Full length human recombinant protein of human Myc (NP_002458) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A