Description
C1q-B polyclonal Antibody | BS6974 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200
Background: C1q, a subcomponent of the classical complement pathway, mediates its activation and thereby plays an important role in immune response. The presence of receptors for C1q on effector cells modulates its activity, which may be Antibody-dependent or independent. Macrophages are the primary source of C1q, and anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. However, its ability to modulate the interaction of platelets with collagen and immune complexes suggests C1q influences homeostasis as well as other immune activities, and perhaps thrombotic complications resulting from immune injury.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: C1q-B pAb detects endogenous levels of C1q-B protein.
Molecular Weight: ~ 28 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: C1QTNF5; CTRP5; DKFZP586B0621; LORD
Immunogen: Recombinant full length Human C1q-B.
Conjugate: N/A
Modification: N/A
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: N/A