LBD
C4orf31 Antibody (N-term) [APR11261G]
- SKU:
- LBD-APR11261G
- Availability:
- Usually ships in 5 working days
Description
C4orf31 Antibody (N-term) [APR11261G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This C4orf31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids of human C4orf31.
Cellular Localisation: Secreted
Molecular Weight: 64673
Clone: Polyclonal
Gene Name: NDNF
Gene ID: 79625
Function: Secretory protein that plays a role in various cellular processes (PubMed:20969804, PubMed:24706764, PubMed:31883645) . Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus (PubMed:31883645) . Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system (PubMed:20969804, PubMed:31883645) . May also act through the regulation of growth factors activity and downstream signaling (PubMed:31883645) . Also regulates extracellular matrix assembly and cell adhesiveness (By similarity) . Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms (PubMed:24706764) .
Summary: Tissue Location: Expressed in neurons along the gonadotropin- releasing hormone (GnRH) expressing neurons migratory route
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Synonyms: Protein NDNF, Neuron-derived neurotrophic factor, NDNF, C4orf31