Description
C7280948 is an inhibitor of PRMT1 (Protein arginine N-methyltransferase 1) with IC₅₀ value of 12.75 μM. It serves as a useful tool in studying the role of PRMT1 in epigenetics. PMRT1 has been reported to activate estrogen and androgen receptors and is an essential component for oncogenic transformation induced by a mixed lineage leukemia (MLL) complex.
C7280948 is an inhibitor of PRMT1 (Protein arginine N-methyltransferase 1) with IC₅₀ value of 12.75 μM. It serves as a useful tool in studying the role of PRMT1 in epigenetics. PMRT1 has been reported to activate estrogen and androgen receptors and is an essential component for oncogenic transformation induced by a mixed lineage leukemia (MLL) complex.
Alternate Name/Synonyms: 4-amino-N-phenethylbenzenesulfonamide
Appearance: Off-white solid
Formulation: N/A
CAS Number: 587850-67-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₄H₁₆N₂O₂S
Molecular Weight: 276.35
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>25 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A PRMT1 (Protein arginine N-methyltransferase 1) inhibitor
MDL Number:
PubChem CID: 833539
SMILES: C1=CC=C(C=C1)CCNS(=O)(=O)C2=CC=C(C=C2)N
InChi: 1S/C14H16N2O2S/c15-13-6-8-14(9-7-13)19(17,18)16-11-10-12-4-2-1-3-5-12/h1-9,16H,10-11,15H2
InChi Key: BYWZPUPRVIECEC-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |