CACNA1E Antibody | 13-497

CACNA1E Antibody | 13-497 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2014-2313 of human CACNA1E (NP_001192222.1) .

Research Area: Cancer, Neuroscience, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: 293T

Positive Control 3: Mouse brain

Positive Control 4: Mouse liver

Positive Control 5: Rat brain

Positive Control 6: N/A

Molecular Weight: Observed: 290kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: BII, CACH6, CACNL1A6, Cav2.3, EIEE69, gm139, voltage-dependent R-type calcium channel subunit alpha-1E, brain calcium channel II, calcium channel, L type, alpha-1 polypeptide, calcium channel, R type, alpha-1 polypeptide, voltage-dependent calcium channel alpha 1E subunit, voltage-gated calcium channel alpha subunit Cav2.3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.