CAD Protein Antibody| F41205-0.08ML/F41205-0.4ML/RQ4026

CAD Protein Antibody| F41205-0.08ML/F41205-0.4ML/RQ4026 | Gentaur UK, US & Europe Distribution

Background: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse

Application: WB, IHC, FACS, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50, Flow Cytometry: 1:10-1:50

Application Note: Titration of the CAD antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This CAD antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 780-809 from the human protein was used as the immunogen for this CAD antibody.

Storage: Aliquot the CAD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A