CALD1 Polyclonal Antibody | E-AB-60930

CALD1 Polyclonal Antibody | E-AB-60930 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CALD1, CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22, caldesmon

Application: WB, IHC

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Signal Transduction

Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human CALD1 (NP_004333.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 61 kDa/62 kDa/64 kDa/65 kDa/93 kDa

Molecular Weight(Observed): 85 kDa