LBD
CALHM3 Antibody (N-term) [AMM08603G]
- SKU:
- LBD-AMM08603G
- Availability:
- Usually ships in 5 working days
Description
CALHM3 Antibody (N-term) [AMM08603G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CALHM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from the N-terminal region of human CALHM3.
Cellular Localisation: Basolateral cell membrane {ECO:0000250|UniProtKB:J3QMI4}; Multi-pass membrane protein
Molecular Weight: 38496
Clone: Polyclonal
Gene Name: CALHM3 (HGNC:23458)
Gene ID: 119395
Function: Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs) . CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
Summary: Tissue Location: Specifically expressed in circumvallate taste bud cells.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Calcium homeostasis modulator protein 3, Protein FAM26A, CALHM3, FAM26A