Candesartan | B3231

Candesartan is an oral angiotensin II receptor blocker (IC50 values are 1.12 and 2.86 nM in bovine adrenal cortex and rabbit aorta, respectively). It is available as a pro-drug, candesartan cilexetil, which undergoes hydrolysis in the gastrointestinal tract during absorption to its active form. Displays antihypertensive effects in animal models.

Candesartan is an oral angiotensin II receptor blocker (IC50 values are 1.12 and 2.86 nM in bovine adrenal cortex and rabbit aorta, respectively). It is available as a pro-drug, candesartan cilexetil, which undergoes hydrolysis in the gastrointestinal tract during absorption to its active form. Displays antihypertensive effects in animal models.

B3231 | Candesartan DataSheet

Alternate Name/Synonyms: CV-11974,1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid

Appearance: White solid

Formulation:

CAS Number: 139481-59-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₂₀N₆O₃

Molecular Weight: 440.45

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: >40 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An oral angiotensin II receptor blocker

MDL Number:

PubChem CID: 2541

SMILES: CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O

InChi: InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)

InChi Key: HTQMVQVXFRQIKW-UHFFFAOYSA-N