Candida albicans/Candida glabrata /Candida krusei RT-PCR (CE) | F3-FRT

Candida albicans/Candida glabrata /Candida krusei RT-PCR (CE) | F3-FRT is available for delivery

Multiplex Real Time PCR test for the qualitative detection of Candida albicans, Candida glabrata, and Candida krusei

Storage & Shipping :

The kit can be shipped at 2-8°C for 3-4 days but should be stored at 2-8°C and -20°C immediately on receipt.

Candida albicans/Candida glabrata /Candida krusei RT-PCR (CE) F3-FRT DataSheet

INTRODUCTION

Candida albicans is a diploid fungus that grows both as yeast and filamentous cells and a causal agent of opportunistic oral and genital infections in humans. Systemic fungal infections (fungemias) including those by C. albicans have emerged as important causes of morbidity and mortality in immunocompromised patients (e.g., AIDS, cancer chemotherapy, organ or bone marrow transplantation). In addition, hospital-acquired infections by C. albicans have become a cause of major health concerns.

Candida glabrata is a haploid yeast of the genus Candida, previously known as Torulopsis glabrata. Until recently, C. glabrata was thought to be a primarily non-pathogenic organism. However, with the ever increasing population of immunocompromised individuals, trends have shown C. glabrata to be a highly opportunistic pathogen of the urogenital tract, and of the bloodstream (Candidemia). It is especially prevalent in HIV positive people.

Candida krusei is a budding yeast (a species of fungus) involved in chocolate production. Candida krusei is an emerging fungal nosocomial pathogen primarily found in the immunocompromised and those with hematological malignancies. It has natural resistance to fluconazole, a standard antifungal agent. It is most often found in patients who have had prior fluconazole exposure, sparking debate and conflicting evidence as to whether fluconazole should be used prophylactically. Mortality due to C. krusei fungemia is much higher than the more common C. albicans.

INTENDED USE

Kit Candida albicans/ Candida glabrata/ Candida krusei Real-TM is a multiplex Real Time PCR test for the qualitative detection of Candida albicans, Candida glabrata, and Candida krusei DNA in the human clinical materials.

PRINCIPLE OF ASSAY

Kit Candida albicans/ Candida glabrata/ Candida krusei Real-TM is based on two major processes: isolation of DNA from specimens and Real Time amplification.